Visual Information Present in Infragranular Layers of Mouse Auditory Cortex

• DOI: 10.1523/jneurosci.3102-17.2018
• Publication Date: 2018-02-13T17:55:18Z
• Authors: Ryan J. Morrill; Andrea R. Hasenstaub
• Keywords: Stimulus (psychology); Stimulus modality; Orientation column

The cerebral cortex is a major hub for the convergence and integration of signals from across sensory modalities; cortices, including primary regions, are no exception. Here we show that visual stimuli influence neural firing in auditory awake male female mice, using multisite probes to sample single units multiple cortical layers. We demonstrate both secondary cortex. then determine laminar location recording sites through electrode track tracing with fluorescent dye optogenetic identification layer-specific markers. Spiking responses stimulation occur deep particularly prominent layer 6. Visual modulation rate occurs more frequently at areas secondary-like than those primary-like responses. Auditory drifting gratings not orientation-tuned, unlike deepest layers thus appear be an important locus cross-modal SIGNIFICANCE STATEMENT often considered its most enigmatic, possessing wide range cell morphologies atypical that, mouse cortex, these represent convergence, containing many responsive stimuli. Our results suggest this signal conveys presence timing stimulus rather specifics about stimulus, such as orientation. These shed light on how what types information integrated earliest stages processing.