Demographic Inference Reveals African and European Admixture in the North AmericanDrosophila melanogasterPopulation

• DOI: 10.1534/genetics.112.145912
• Publication Date: 2012-11-14T01:14:24Z
• Authors: Pablo Duchen; Daniel Živković; Stephan Hutter; Wolfgang Stephan; Stefan Laurent
• Keywords: Approximate Bayesian Computation; Population bottleneck; Demographic history; Population Genetics

Abstract Drosophila melanogaster spread from sub-Saharan Africa to the rest of world colonizing new environments. Here, we modeled joint demography African (Zimbabwe), European (The Netherlands), and North American (North Carolina) populations using an approximate Bayesian computation (ABC) approach. By testing different models (including scenarios with continuous migration), found that admixture between Europe most likely generated population, estimated proportion ancestry 15%. We also revisited ancestral population (Africa) found—in contrast previous work—that a bottleneck fits history Zimbabwe better than expansion. Finally, compared site-frequency spectrum analytical predictions under model.