The prevalence of extended-spectrum beta-lactamase-producingEscherichia coliandKlebsiella pneumoniaeamong clinical isolates from a general hospital in Iran

• DOI: 10.1556/amicr.56.2009.1.7
• Publication Date: 2009-03-27T01:01:30Z
• Authors: Bibi Bazzaz; Mahboobeh Naderin...; Amir Mohamadpoor; Zahra Farshadzadeh; Samaneh Ahmadi; Forough Yousefi
• Keywords: Aztreonam; Beta-lactamase; Agar diffusion test; Isolation

This study was conducted at a 900+ bed general teaching hospital, from May to September 2007, in Iran. The aim of this determine the prevalence extended-spectrum beta-lactamase (ESBL) producing Escherichia coli and Klebsiella pneumoniae their antimicrobial pattern. Kirby-Bauer disk diffusion method phenotypic confirmatory test were performed for each isolate. total 206 isolates including 106 E. 100 K. collected which 122 (59.2%) ESBL positive. ESBL-producing strains 59.2% (122/206). All susceptible imipenem. Among isolates, sensitivity 3.3% 61.5% ampicillin aztreonam. From female (136), 59.5% male (70), 58.6% ESBL-producers. Ratios hospitalized patients out-patients 94/28 group. number according isolation sites showed significant difference between ESBL-producers non-producers blood samples ( P <0.05). shows that Iran is high. It seems necessary clinicians medical community personnel be fully aware microorganisms.