Study of the retention behavior of newly synthesizeds-triazine derivatives in RP TLC systems, and the lipophilicity of the compounds

• DOI: 10.1556/jpc.16.2003.6.4
• Publication Date: 2007-03-26T19:17:41Z
• Authors: Nada. Perišić-Janjić; Bratislav. Jovanović; Nataša Janjić; Olga Rajković; Dušan Antonović
• Keywords: Lipophilicity; Triazine; Tetrahydrofuran

The chromatographic behavior of nine newly synthesized s -triazines has been studied by thin-layer chromatography on C 18 /UV 254 , HPTLC Nano-Sil-CN/UV 254 , and HPTLC Nano-Sil NH 2 /UV 254 HPTLC plates. Relationships between the R M values of the s -triazines and mobile phase composition were determined for water-tetrahydrofuran, water-dioxane, and water-acetonitrile mobile phases. Retention data observed with different mobile-phase modifiers and different stationary phases were compared. The correlation between the retention of the compounds in reversed-phase liquid chromatography and their octanol-water partition coefficients, expressed as log P , was examined.