Artemisia annua (Qing Hao): Solved and Adaptively Met the Drug Resistance Challenge by Plasmodium Malaria Parasite. It’s other Chemotherapeutic attempt against Cancer; and Overall Implications on Public Health
Artemisia annua
Malarial parasites
DOI:
10.15580/gjbhs.2016.1.101816180
Publication Date:
2018-11-04T23:49:55Z
AUTHORS (6)
ABSTRACT
The plant herb Artemisia annua (Qing Hao) has been used in China for over 400years to treat malaria disease, which a mostly higher prevalence the tropics where it is more endemic.Also, kill parasitic worms, as anti-microbial agents, and found non-medicinal uses United States Europe.The active anti-malarial compound A. called Artemisinin was isolated 1970s. Evidence of drug resistance by parasite based monotherapy some Southeast Asian countries propelled development introduction combination therapies (ACTs) WHO now encourages monotherapy.A research team appear have pioneered "chemotherapeutic revolution Cancer treatment" involving use compounds, with reported successes on human breast cancer cells in-vitro-from bench work, cancerous were killed within hours treatment an compound.With work first genetic map done published Kingdom team, on-going funded studies develop effective non-synthetic semi-synthetic analogues underway, plethora opportunities stand become available be exploited utilized other investigations; but whether this would translate authenticated that could do well or/and pass anti-cancer screening yardsticks related National Drug approving standardization agencies remains real task.Worthy note discovery new plants screened show properties battle cancer.This should complement efforts through artemisinin its derivative compounds cancer.These are part multi-faceted attempts man against "these strange deranged grow sake growth no clearly constituted means modulating growths".The historical developments Artemisia/artemisinin various derivatives, chemical shortcomings improvements relation elucidated article.
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