The effect of acute exercise session on thyroid hormone economy in rats

• DOI: 10.1677/joe-08-0174
• Publication Date: 2008-06-07T00:55:07Z
• Authors: Rodrigo Soares Fo...; Daniele Leão Ignácio; Álvaro Souto Padron; Ramon Peçanha; Michelle Porto Ma...; Doris Rosenthal; João Pedro Saar W...; Denise P Carvalho
• Keywords: Iodothyronine deiodinase; Treadmill

The hypothalamic–pituitary–thyroid axis is affected by acute exercise, but the mechanisms underlying thyroid function changes after exercise remain to be defined. aim of this study was elucidate effects a session on treadmill at 75% maximum oxygen consumption rats. Male Wistar rats were divided into five groups: control (without exercise), and killed immediately (0 min) or 30, 60, 120 min end session. A significant increase in serum tri-iodothyronine (T 3 ) occurred with gradual decrease thereafter, so that T significantly lower than controls. Total thyroxine 4 increased progressively reaching values higher group min. /T ratio decreased 60 indicating impaired -to-T conversion. Liver type 1 deiodinase activity (D1) min, while pituitary D1 from 30 only exercise. Brown adipose tissue (BAT) 2 (D2) D2 remained unchanged. No change thyrotropin detected, corticosterone Our results demonstrate liver BAT might involved conversion detected an treadmill.