Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion

• DOI: 10.1682/jrrd.2012.08.0147
• Publication Date: 2013-11-15T19:01:47Z
• Authors: Natalia C. Rodrigues; Lívia Assis; Kelly R. Fernandes; Angela Magri; Daniel A. Ribeiro; Roberta Brunelli; Daniela C. C. Abreu; Ana Claudia M. Renno
• Keywords: Muscle tissue; Granulation tissue

The aim of this study was to evaluate the effects 660 nm low-level laser therapy (LLLT) on muscle regeneration after cryolesion in rat tibialis anterior muscle. Sixty-three Wistar rats were divided into a control group, 10 J/cm(2) laser-treated and 50 group. Each group formed three subgroups (n = 7 per group), animals sacrificed 7, 14, or 21 d lesion. Histopathological findings revealed lower inflammatory process groups d. After 14 d, irradiated at both fluences showed higher granulation tissue, new fibers, organized structure. full tissue repair observed all groups. Moreover, smaller necrosis area first experimental period evaluated. MyoD immunoexpression treated postinjury. Myogenin detected fluence increased number blood vessels These results suggest that LLLT, fluences, positively affects injured skeletal rats, accelerating muscle-regeneration process.