C-reactive protein postoperative values to predict clinically relevant postoperative pancreatic fistula after distal pancreatectomy

• DOI: 10.17235/reed.2022.8795/2022
• Publication Date: 2022-06-22T11:02:34Z
• Authors: Luz Divina Juez; Elena Payno; Irene de Vicente; Eduardo Lisa; José Manuel Molina; Eduardo Lobo Mart...; José María Fernán...; Alfonso Sanjuanbe...
• Keywords: Pancreatic fistula; Univariate analysis

IntroductionDespite significant medical and technological advances, the incidence of Postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP) is reported to be between 3-45%.The main objective our study was analyse early post-surgical risk factors for developing POPF DP. Material methodsA retrospective observational conducted on a prospective basis patients undergoing PD in tertiary hospital from January 2011 December 2021.Sociodemographic, preoperative analytical, tumour-related postoperative complications variables were analysed. ResultsOf 52 analysed, 71.8% sample had drains amylase elevation; however, 25.7% total Grade-B and/or Grade-C POPF.Univariate logistic regression with studied showed following as B-C o clinically relevant POPF: values drainage at 5 th POD [p=0.097;1.01(1-1.01)] BMI [p=0.015;] CRP value 3 rd [p=0.034;1.01 (1.01-1.02)].The ROC curve an area under 0,764 (CI 95% 0,6-0,93) best cut-off point 190 mg/L (Sensitivity 89% Specificity 67%). ConclusionsCRP predictive factor DP.Early detection based these characteristics could have impact their management.