Brusellozis: 127 Olgunun değerlendirmesi

• DOI: 10.17343/sdutfd.72102
• Publication Date: 2009-03-18
• Authors: Arıbaş, Emel; Yılmaz, Abdullah; Bitirgen, Mehmet
• Keywords: 616; 610

SuleymanDemirel Universitesi TIP FAKULTESI DERGISI: 2001 ; 8(1) Brusellozis: 127 Olgunun degerlendirmesi Emel Turk Aribas , Abdullah Yilmaz, Mehmet Bitirgen Ozet Bu calismada, bruselloz tanisi ile izlenen 127 olguda bulas yollan, klinik, laho¬ra t uva r ve tedavi ozellikleri degerlendirildi. Yaslan 14-86 (ort:45.79) arasinda degisen olgularin 72 (%56.69)' i kadin, 55 (%43.30)' u erkek idi. Olgularin 76 (%59.83)' smda bulas yolu olarak hayvancilikla ugrasma, cig sut ve sut urunleri tuketimi saptandi. En sik rastlanan yakinmalar; ates (%50.39), artralji (%46.45), halsizlik (%39.37) ve ter¬leme (%30.70) olarak belirlendi. Fizik muayene bulgusu olarak en sik saptanan anor¬mallikler sirasiyla ates (%33.07), hepatomegali (%19.6), artrit (%J4.17) ve splenome-gali (%11.81) idi. Sadece 3 olguda menenjit ve birinde orsit vardi. Olgularin tamaminda STA testi > 11160 bulundu ve % 4.72' sinde Britcella spp. izole edildi. Tedavide 93 has¬taya doksisiklin + rifampisin ve 30 olguya doksisiklin +•- streptomisin 6 hafta sureyle uygulandi. Doksisiklin + rifampisin uygulanan hastalarda relaps %5.3 ve doksisiklin + streptomisin uygulananlarda %3 olarak saptandi. Aralarindaki fark istatistiksel olarak anlamli degildi. Anahtar Kelimeler: Brusellozis,Tani, Komplikasyon, Tedavi Abstract Brucellosis : Evaluation Of 127 Cases in this study, 127 patients diagnosed as brucellosis were evaluated about trans-mission routes, clinical, laboratory and therapeutic features. Ranging between 14-86 (mean:45.79) years, 72 (%56.96) of the patients werefemale, 55 (%43.30) were male. in 76 (%59.83) of the cases, infection was releated with stock raising and consuming unpasteurised milk and milk products. The most freauently complaints detected were fever (%50.39), arthralgy (%40.45), lack of appetite (%39.37) and sweating (%30.70). As physical examination findings, the most frequently abnormaUties were detected as fever (%33.07), hepatomegaly (%19.60), arthritis (%14.17), splenomegaly (%11.81). Only in 3 cases meningitis and in one orchitis had developed as complication of brucel¬losis. in ali cases the standart tube aglutination (STA) test ti ter was found > 1/160 and in %4.72 of the cases Brucella spp. could be isolated. 93 patients received a combina-tion therapy composed of doxycycline plus rifampinfor 6 weeks and 30 cases used doxy-cycline plus streptomycin for 6 weeks. The patients who received doxycycline plus rifampin had a relaps rate of%5.3, wherease the rate of the other groitp which received doxycycline plus streptomycin w as found as %10. The difference between two groups was not statistically significant (p>0.05). Key Words: Brucellosis,Diagnosis, Complications, Treatment