Identification of antimicrobial peptides in Lycopersicon esculentum genome

• DOI: 10.17537/icmbb18.13
• Publication Date: 2018-11-15T08:16:00Z
• Authors: A.S. Kovtun; E.A. Istomina; M.P. Slezina; T.I. Odintsova
• Keywords: Identification; Lycopersicon

Antimicrobial peptides (AMPs) constitute an important part of the plant immune system protecting plants from invading pathogens.Some antimicrobial are also active against human pathogenic microorganisms, including antibiotic-resistant strains that makes these molecules promising candidates for design next-generation drugs to treat infections.Plants represent a valuable source effective yet poorly explored peptides.An efficient pipeline highthroughput in silico detection Lycopersicon esculentum genome has been developed.As many as 66 putative AMPs were revealed L. genome.The discovered belong four AMP families: defensins, thionins, lipid-transfer proteins, and hevein-type peptides.The vast majority newly have not annotated so far.Further functional analysis detected will evaluate their potential novel drug leads biopesticides practical application agriculture medicine.