Scavenging Activity on Reactive Oxygen Species with Biological Relevance by Varronia curassavica

• DOI: 10.17807/orbital.v15i2.17939
• Publication Date: 2023-07-17T02:12:12Z
• Authors: Gabriela Brasil ...; Flavio Alexandre ...; Renata Pires Assis; Juhan Augusto Sc...; Christiane Pienn...; Iguatemy Lourenç...; Vera Lucia Borge...; Paulo Riceli; Guilherme Zocolo; Marcos Antonio C...; André Gonzaga do...
• Keywords: ABTS; Rosmarinic acid; Trolox; EC50

Varronia curassavica Jacq. is a medicinal plant found in Brazil used as anti-inflammatory. Here, we investigated the vitro antioxidant activity of 70 % ethanol extract V. leaves on synthetic radicals (ABTS•+/DPPH•) and reactive oxygen species (O2•-, ROO•, HOCl/OCl-, H2O2), besides its cytotoxicity. The was characterized by UPLC-ESI-QToF-MSE annotated compounds were one hydroxybenzoic acid, five phenylpropanoids, three glycosylated quercetin derivatives, being main compound rosmarinic acid or isomer. very promising all tests, highlighting capture O2•-, which EC50 value times lower than Trolox. This may be due to presence major compounds, phenolic compounds. also presented low Thus, from has great potential an antioxidant.