SEARCHING FOR NEW FACTORS WHICH INFLUENCE TRANSLATION TERMINATION IN YEASTSACCHAROMYCES CEREVISIAE

• DOI: 10.17816/ecogen11142-48
• Publication Date: 2016-04-19T14:03:46Z
• Authors: Svetlana Yevgenye...; Olga Anatolyevna ...; Olga Leonidovna A...; Galina Anatolyevn...

In the yeast Saccharomyces cerevisiae translation termination factor eRF1 is encoded by essential gene SUP45. Here we applied multicopy library to identify a new which interacts with release in cerevisiae. We identified EСM23 whose overexpression decreased viability of sup45 nonsense mutants. also showed that ECM23 had antisuppressor effect but level protein was same as wild-type cells. The mechanisms influence mutants are discussed