Association of cardiovascular disease with hospital mortality in COVID-19 patients

• DOI: 10.18087/cardio.2023.10.n2408
• Publication Date: 2023-11-16T16:02:23Z
• Authors: N. V. Pogosova; M. V. Ezhov; I. V. Barinova; A. K. Ausheva; D. T. Kuchiev; A. B. Popova; A. A. Arutyunov; S. A. Boytsov
• Keywords: Male; Aged, 80 and over; Heart Failure; Cardiovascular Diseases; Risk Factors; Myocardial Infarction; Humans; COVID-19; Female; Hospital Mortality; 3. Good health

Aim. To evaluate the relationship between in-hospital mortality of patients with COVID-19 and history cardiovascular disease (CVD) using data from Russian registry COVID-19. Material methods. This study included 758 (403 men, 355 women) aged 18 to 95 years (median, 61 years), successively hospitalized in COVID hospital Chazov National Medical Research Center Cardiology April through June 2020. Death predictors were studied single- multivariate regression analyses SPSS Statistics, Version 23.0 software. Results. During stay hospital, 59 (7.8 %) died, 677 (89.3 discharged, 22 (2.9 transferred other hospitals. The univariate analysis showed that increase age per decade was associated a 92% risk death [relative (RR), 1.92; 95% confidence interval (CI), 1.58-2.34; p <0.001], an number CVDs increases by 71% (RR 1.71; CI 1.42–2.07; p<0.001). presence one or more specific diseases [atrial fibrillation, chronic heart failure (CHF), ischemic disease, myocardial infarction, cerebrovascular accidents], as well diabetes mellitus higher fatal outcome during hospitalization for any CVD increased 3.2 times. However, when model adjusted sex, this association lost its strength, only CHF 3-fold (RR, 3.16; % CI, 1.64-6.09; p=0.001). Age another independent predictor 1.05; 1.03-1.08; < 0.001). Conclusion. A severity are COVID-19; 80 older CHF.