Effect of the “door-to-balloon” time on the results of treatment of patients with ST-segment elevation myocardial infarction, depending on the duration of the pre-hospital delay

• DOI: 10.18087/cardio.2023.6.n2245
• Publication Date: 2023-07-20T13:43:23Z
• Authors: I. S. Bessonov; S. S. Sapozhnikov; A. A. Shadrin; M. G. Kashtanov; S. V. Popov
• Keywords: Door-to-balloon

Aim To analyze the effect of door-to-balloon time on treatment outcomes in patients with acute ST-segment elevation myocardial infarction (STEMI) depending duration pre-hospital delay. Material ad methods The study used data hospital registry percutaneous coronary interventions (PCI) STEMI from 2006 through 2017. analysis included 1333 patients. All were divided into two groups. first group 574 (43.1%) pain syndrome onset to admission was ≤120 min. second consisted 759 (56.9 %) delay exceeding 120 Results analyzed for each time, ≤60 min or >60 In prehospital less than and vs. min, following observed: decreased in-hospital mortality (1.3 % 6.8 %, p=0.001), reduced incidence major adverse cardiac effects (МАСЕ) (3.2 8.3 p=0.008), no-reflow phenomenon (3.9 9.4 p=0.007). Also, immediate angiographic success PCI more frequently achieved these patents (94.5 87.5 p=0.003). addition, a higher ejection fraction noted at discharge (48 [43; 51] 46 [42; р=0.038). Comparison between groups different (≤60 min) >120 did not show any significant intergroup differences. According multivariate analysis, predict mortality. There strong correlation total ischemia (r=0.87; р<0.001) while moderate (r=0.41; р<0.001). At same there no time. Conclusion onset, decrease associated better outcome treatment. When influence outcome. strongly correlated ischemia.