Autosomal InDel polymorphisms for population genetic structure and differentiation analysis of Chinese Kazak ethnic group

• DOI: 10.18632/oncotarget.17838
• Publication Date: 2017-05-13T08:02:18Z
• Authors: Tingting Kong; Yahao Chen; Yuxin Guo; Yuanyuan Wei; Xiaoye Jin; Tong Xie; Yuling Mu; Qian Dong; Shaoqing Wen; Boyan Zhou; Li Zhang; Chunmei Shen; Bofeng Zhu
• Keywords: Indel; INDEL Mutation

// Tingting Kong 1, 2, 3 , Yahao Chen 4 Yuxin Guo 5 Yuanyuan Wei 2 Xiaoye Jin Tong Xie Yuling Mu Qian Dong Shaoqing Wen 6 Boyan Zhou 6, 7 Li Zhang 8 Chunmei Shen 9 and Bofeng Zhu 1 Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College Stomatology, Xi'an Jiaotong University, Xi'an, P. R. China Clinical Research Center Dental Maxillofacial Diseases, Department Forensic Genetics, School Medicine, Southern Medical Guangzhou, Center, The First Affiliated Hospital Xinjiang Urumqi, & Forensics, University Health Science State Genetic Engineering MOE Contemporary Anthropology, Life Sciences Institutes Biomedical Sciences, Fudan Shanghai, Institute Biostatistics, Gastroenterology, Second Brain Behavioral Normal Correspondence to: Zhu, email: [e-mail] Keywords: Kazak group, InDel, population genetics, interpopulation differentiation, phylogenetic tree Received: March 08, 2017 Accepted: April 12, Published: May ABSTRACT In the present study, we assessed genetic diversities Chinese ethnic group on basis 30 well-chosen autosomal insertion deletion loci explored relationships between 23 reference groups. We detected level expected heterozygosity ranging from 0.3605 at HLD39 locus to 0.5000 HLD136 observed 0.3548 0.5283 locus. combined power discrimination exclusion all in studied were 0.999999999999128 0.9945, respectively. dataset generated this study indicated panel InDels was highly efficient forensic individual identifcation but may not have enough paternity cases. results differentiations, PCA plots, trees STRUCTURE analyses showed a close affiliation Uigur group.