[Clinical therapy of Zisheng decoction recipe for chronic atrophic gastritis with intestinal metaplasia].

• DOI: 10.19540/j.cnki.cjcmm.20170919.004
• Publication Date: 2017-12-01
• Authors: Xiuxia Wu; Xian Li; Zhongqin Dang; Wen-Zhao Luo; Chang-Pu Zhao; Kun Yu
• Keywords: Decoction; Atrophic gastritis; Intestinal metaplasia; Famotidine; Therapeutic effect

To explore the therapeutic effect and security of Zisheng decoction recipein treatment chronic atrophic gastritis (CAG) with intestinal metaplasia(IM). A total 147 eligible cases were randomly divided into traditional Chinese medicine group, Western group combined group,47 in each group. recipe, famotidine, as well recipe + famotidine respectively given above three groups, a course 30 d. The symptoms medicine, pathological score gastric mucosa negative rate Helicobacter pylori before after observed group.The changes pepsinogen Ⅰ (PGⅠ), Ⅱ (PGⅡ), gastrin-17 (GAS-17) endothelin-1 (ET-1)were also detected to compare efficient safety indexes groups. was better than groupand effective (P<0.05), pylori, serum improvement (P<0.05). TCM symptom more obvious In comparison ofincidence complications,heart, liver renal dysfunction, (2 case,4.8%)< (7 case,15.2%) <the (20 case,41.3%) blood urine routine: case,16.7%)< (14 case,30.4%) < (24 case,52.2%) (P<0.05).The results showed that there no significant difference between CAG IM, indicating effective; meanwhile, it had higher famotidine. synergistic can reverse certain extent, alone alone.