[Morphological Characteristics of Bone Marrow Cells in Patients with EB Virus Infection].

• DOI: 10.19746/j.cnki.issn.1009-2137.2022.03.039
• Publication Date: 2022-06-01
• Authors: Liyan He; Yang Zheng; Chunni Huang; Jian Huang
• Keywords: Lymphoid hyperplasia

Review and analyze the characteristics of bone marrow cell morphology in patients with Epstein-Barr virus (EBV) infection, explore diagnostic value for early identification EBV infection.A total 33 EBV-DNA positive detection First Affiliated Hospital Guangxi Medical University from January 2018 to May 2021 were collected as research objects. Bone peripheral blood analysis performed, significance disease diagnosis was analyzed by statistical methods.The sampling satisfaction infection 100%. In clinical all cases, 7 cases IM, 17 EBV-HLH, 3 lymphoma, 2 EBV-associated lymphoid hyperplasia, 4 not diagnosed. Among them, 31 had active hyperplasia or above, 26 granulocytic 21 erythroid megakaryocyte production platelet function decreased. The abnormal components mainly indude atypical lymphocyte cells (33 cases), hemophagocytic (22 histiocyte (10 cases).According proliferation granulocytes, erythrocytes megakaryocytes marrow, emergence such lymphocytes, hemophagocyte, histiocyte. morphological examination can indicate possibility which is certain infection.EB病毒感染患者骨髓细胞形态学特点分析.回顾分析EB病毒（EBV）感染患者的骨髓细胞形态学的特征，探讨骨髓细胞形态学对早期识别EBV感染的诊断价值.收集广西医科大学第一附属医院2018年1月至2021年5月EBV-DNA检测阳性的患者33例作为研究对象，进行骨髓细胞形态学检查、外周血细胞分析，用统计学方法分析其在疾病诊断中的意义.EBV感染患者取材33例，满意度100%。临床诊断IM 7例，EBV-HLH 17例，淋巴瘤3例，EBV相关淋巴增殖性疾病2例，未能明确诊断4例。其中31例出现骨髓增生活跃或以上，26例出现粒系增生活跃或以上，21例出现红系增生活跃或以上，17例出现巨核细胞产血小板功能减低。骨髓异常成分主要有异型淋巴细胞（33例），噬血细胞（22例），异常组织细胞（10例）.根据骨髓粒、红、巨三系造血细胞增生情况的改变，以及异型淋巴细胞细胞、噬血细胞、异常组织细胞等异常成分的出现，骨髓细胞形态学检查可以提示感染EBV的可能性，对早期识别EBV感染有一定的诊断价值.