Impact of aspirin on pancreatic cancer in the elderly: analysis of socioeconomic status and outcomes of national matched cohorts.

• DOI: 10.20524/aog.2024.09179
• Publication Date: 2024-11-21
• Authors: Thanathip Suengha...; Tuntanut Lohawatc...; Narathorn Kultham...; Pojsakorn Danpani...; Kanokphong Suparan; Natchaya Polpichai; Jerapas Thongpiya; Sakditad Saowapa

Pancreatic cancer is a neoplastic condition with high disease burden. It projected to be the second most common cause of cancer-related deaths by 2030. However, evidence supporting long-term use aspirin in prevention and treatment remains insufficient. We aimed investigate association between pancreatic outcomes elderly population group. The 2020 National Inpatient Sample was used records patients admitted cancer, identified ICD-10 CM codes. data were categorized based on use. assessed inpatient mortality as primary outcome, while secondary included costs length stay, well other complications. 19,249 hospitalizations aged over 60 years. mean age 73.8 years, 49.3% male. In survey multivariate logistic linear regression model, adjusting for patient characteristics hospital factors, associated lower (adjusted odds ratio [aOR] 0.55, 95% confidence interval [CI] 0.33-0.92; P=0.023), shorter stay (beta coefficient -0.52, 95%CI -0.93 -0.11; P=0.012), acute kidney injury (aOR 0.76, 0.59-0.98; P=0.039), shock 0.23, 0.06-0.78; P=0.019]. Post-propensity matching revealed similar patterns. Long-term rate clinical hospitalized cancer. etiologies behind this relationship should explored view better understanding.