Pain Coping Strategies In Pediatric Patients With Acute Leukemias In The First Month Of Therapy: Effects Of Treatments And Implications On Procedural Analgesia

• DOI: 10.20944/preprints202201.0451.v1
• Publication Date: 2022-02-01T11:53:38Z
• Authors: Marta Tremolada; Giulia Tasso; Roberta Maria Inc...; Manuela Tumino; Maria Caterina Putti; Alessandra Biffi; Marta Pillon
• Keywords: Mucositis; Dose

Children with leukaemia experience difficulties adapting to medical procedures and the chemotherapy’s adverse effects. Study’s objectives were identify which coping strategies could be associated treatments’ factors dosage of sedation analgesic drugs during bone marrow aspirates. 125 patients (M = 6.79 years; SD 3.40), majority acute lymphoblastic leukemia (90.4%) their parents received, one month after diagnosis, PPCI. Data on severe treatment effects in sedation-analgesia also collected. An ANCOVA model (R2=0.25) showed that, weighing age factor (F=3.47; df=3; p=0.02), number episodes fever (F=4.78; df=1; p=0.03), nausea (F=4.71; p=0.03) mucositis (F=5.81; p=0.02) influenced use distraction. Cognitive self-instructions (R2=0.22) by hospitalizations (F=5.14; (F=8.48; p=0.004) child’s (F=3.76; p=0.01). who sought parental support more frequently (F=9.7; df=2; p=0.0001) tended not succumb a catastrophic attitude (F=13.33; p=0.001) induction phase required lower drug dosages, especially propofol. The clinical application these results encourage cognitive search for social support.