Vector Competence of <em>Aedes albopictus</em> for Yellow Fever Virus: Risk of Reemergence of Urban Yellow Fever in Brazil

• DOI: 10.20944/preprints202303.0330.v1
• Publication Date: 2023-03-21T01:12:05Z
• Authors: Rossela Damasceno...; Joaquim Pinto Nun...; Carine Fortes Aragão; Maria Nazaré Oliv...; Milene Silveira F...; Paulo Henrique Go...; Daniel Damous Dias; Pedro Arthur da S...; Roberto Carlos Fe...; Bruno Tardelli Di...; Eliana Vieira Pin...; Lívia Caricio Mar...; Pedro Fernando da...; Ana Cecília Ribei...
• Keywords: 11. Sustainability; 3. Good health

The risk of the emergence and reemergence of zoonoses is high in regions that are under anthropogenic actions, as they contribute to the risk of vector disease transmission. Yellow fever (YF) is among the main pathogenic arboviral disease in the world, and the Culicidae Aedes albopictus has been proposed to have the potential to transmit yellow fever virus (YFV). This mosquito inhabits both urban and wild environments, and under experimental conditions, it has been shown to be susceptible to infection by YFV. In this study, the vector competence of the mosquito Ae. albopictus for the YFV was investigated. Female Ae. albopictus were exposed to non-human primates (NHP) of the genus Callithrix infected with YFV for blood meal. Subsequently, on the 14th and 21st days post infection, the legs, heads, thorax/abdomen and saliva of the arthropods were collected and analyzed by viral isolation and molecular analysis techniques to verify the infection, dissemination and transmission. The presence of YFV was detected in saliva samples through viral isolation and in the head, thorax/abdomen and legs both by viral isolation and by molecular detection. The susceptibility of Ae. Albopictus to YFV confers a potential risk of reemergence of urban YF in Brazil.