Enhanced Antibacterial Properties of Chitosan Fibres

• DOI: 10.20944/preprints202305.1651.v1
• Publication Date: 2023-05-24T02:10:51Z
• Authors: Cesar Hernandez; Zbigniew Draczyński; Dominik Borkowski; Dorota Kaźmierczak
• Keywords: Ursolic acid; Biocompatibility; Chemical modification; Absorbance

Over the years, chitosan has been subject of numerous studies and gained significant popularity as a biomaterial due to its various characteristics, including biocompatibility, biodegradability, bioactivity. In this work, fibres surface was modified with ursolic acid improve their antibacterial properties by wet impregnation method. Five specimens were immersed in (UA) solution for varying immersion times 1, 2, 4, 6, 8 hours. Characterization carried out means FTIR, SEM, UV-Vis spectroscopy; results indicated an ongoing chemical reaction between resulting changes structure. After 2 hours, absorbance ratio remained constant; suggesting that had reached completion structure sample stable. Antibacterial tests performed on against two bacterial strains. The without did not exhibit any noteworthy activity either strain. However, showed almost strong Gram-positive strain, S. aureus. These suggest could have potential applications materials, particularly bacteria.