The Impact of Testicular Hyperthermia, Its Physiological Relevance and the Ability of Antioxidants to Overcome the Condition

• DOI: 10.20944/preprints202309.0882.v1
• Publication Date: 2023-09-14T00:43:56Z
• Authors: Ben J Robinson; Rachel A Ogle; Jacob J Netherton; Ana Izabel Villav...; Allan Gunn; Mark Baker
• Keywords: Semen quality; Sperm Quality

Testicular heat stress is a well described phenomenon that occurs in mammals possess scrotum. Different models to induce testicular hyperthermia, such as surgical cryptorchidism, hot water bath, scrotal insulation or increased environmental temperature have all shown spermatocytes and spermatids are unambiguously affected by high temperature, resulting poor sperm production weeks later. Furthermore, body of evidence suggest the involvement oxidative either major contributory pathway, which gives rise potential overcome this condition. Whilst experimental conclusively show deleterious effect on quality, physiological relevance work still debated. Herein we summarise cohort studies report “season” quality. The data season can affect production, motility morphology depending where was performed. In countries temperatures drop below zero, there showing summer conditions tend improve semen However, sub-tropical countries, some decrease summer, whilst others no change. offer reasonable explanation for apparent controversy present range antioxidant supplements may protection against hyperthermia.