The Impact of Body-Mass-Index on Functional Outcomes and Bleeding Volumes in Patients Suffering Non-Traumatic Intracerebral Haemorrhage

• DOI: 10.20944/preprints202310.0124.v1
• Publication Date: 2023-10-04T05:07:11Z
• Authors: Stefan Wanderer; Attill Saemann; Basil Grüter; Sivani Sivanrupan; Julian Louis Muff; Donato D'Alonzo; Miriam Weiss; Angelo Tortora; Christian Musahl; Gerrit Schubert; Serge Marbacher; Lukas Andereggen
• Keywords: Univariate analysis; Glasgow Outcome Scale; Stroke

The association between obesity and clinical as well radiological outcomes in patients suffering non-traumatic intracerebral haemorrhage (ICH) remains unclear. paradox suggests a protective effect regarding in-hospital mortality. This study evaluates the impact of body mass index (BMI) on functional long-term outcome bleeding volume with ICH. A retrospective cohort including all consecutive spontaneous ICH treated at tertiary referral centre December 2017 June 2021, aged 80 years or younger (n = 218), were included. Patients dichotomized into overweight (OW, BMI ≥ 25 kg/m2) normal weight (NW, < kg/m2). Functional assessed by modified Rankin scale (mRS), extended Glasgow Outcome Scale (GOS-E) National Institutes Health Stroke score (NIHSS) 1, 3, 6 12-months follow-up. Bleeding volumes calculated ABC/2. Univariate multivariate analysis performed to assess predictors favourable long-term. Of 218 (66.04 ± 15.18 years) ICH, 115 (52.75%) OW (29.72 3.82). Female sex (p 0.1), NIHSS 0.69), cardiovascular risk factors 0.55), 0.19), presence anticoagulation 0.67) did not significantly differ NW cohort. At discharge, both cohorts mRS 3.92 2.54 vs. OW, 3.21 2.43, 0.28)). Multivariate revealed that 0.01) was only robust factor predict after 1 year. Our data patients, neither nor patient’s age are negative for Instead, is predicting poor status Therefore, prospective randomized trials analysing this coherence highly warranted.