Interplay Between the Circadian Clock and Sirtuins

• DOI: 10.20944/preprints202409.1202.v1
• Publication Date: 2024-09-18T01:01:14Z
• Authors: Yan Zhuang; Yantong Zhang; Chao Liu; Yingbin Zhong
• Keywords: Clock network; Oscillating gene

The circadian clock is an autonomous timekeeping system evolved by organisms to adapt external changes, regulating a variety of important physiological and behavioral processes. Recent studies have shown that the sirtuin family histone deacetylases involved in expression genes plays role maintaining normal rhythm gene behavior. Moreover, sirtuins are regulated directly or indirectly system. mutual regulation between likely signal transduction metabolism In this review, we discuss molecular mechanisms research progress on intertwined relationship sirtuins, highlighting as links metabolic control rhythms offering our perspectives future developments field.