Improvement in Adenoma Detection Rate with Distal Attachment Device Endo-Wing Assisted Colonoscopy: A Randomized Control Trial

• DOI: 10.20944/preprints202503.0754.v1
• Publication Date: 2025-03-13T00:38:17Z
• Authors: Nabil M Azmi; Prem Kumar; Mazian Ismail; Muhammad Irfan Ab...; Fadzil F

Aim Endo-WingTM is a silicone rubber device with 6 wing-like projections attached at the end of colonoscope that provides superior visualization by flattening colonic fold and helps to maintain central view during withdrawal. This study aims compare adenoma detection rate (ADR) between standard colonoscopy Endo-WingTM-assisted colonoscopy. Methods single-center, single-blind, parallel-group, randomized, actively controlled, exploratory clinical trial conducted July 2019 April 2020. Participants symptomatic colorectal cancer (CRC) or history under active surveillance were included, whilst those known strictures, tumors, colitis, previous polyposis syndrome, had colostomy/ileostomy BPPS score 0 excluded. subsequently randomized receive (n=96), Endo-Wing™ assisted (n=96) in 1:1 ratio using block randomization method varying sizes. The primary endpoint was ADR differences two groups evaluated univariable statistical methods. Results ADR, number adenomas size Endo-Wing™-assisted group significantly higher compared (P=0.005, 0.035, respectively). Caecal intubation rates are similar both (P>0.999). proportions requiring increased sedation (P=0.613). No adverse effects bleeding, perforation dislodgement reported groups. Conclusion: concludes improves