THE EFFECT OF SAFFRON (ITS ACTIVE CONSTITUENT, CROCIN) ON THE CARDIOVASCULAR COMPLICATION AND DYSLIPIDEMIA IN STREPTOZOTOCIN INDUCED DIABETIC RATS

• DOI: 10.21010/ajtcam.v12i5.1
• Publication Date: 2023-06-16T09:11:27Z
• Authors: Eyup Altinoz; Emre Taskin; Zulal Oner; Hulya Elbe; Belkis Atasever A...
• Keywords: Dyslipidemia

Background: Diabetes mellitus (DM) causes serious complications such as coronary heart disease, atherosclerosis, nephropathy, retinopathy
 and neuropathy.
 Materials Methods: Rats were randomly divided into three groups each containing 10 rats; control group, DM group; DM+crocin group.
 Normal saline was administered in the groups, crocin group at a dose of 20 mg/kg bw/day
 for 21 days. Trunk blood hearth tissue collected histopathological biochemical examination.
 Results: led to increment MDA levels (p