MAF proteins: a family of regulating and regulated molecules

• DOI: 10.21037/dmr.2018.10.02
• Publication Date: 2018-11-16T09:39:33Z
• Authors: Maria Maddalena S...; Gavinella Latte; Rosa Maria Pascale
• Keywords: 0303 health sciences; 03 medical and health sciences; 3. Good health

The proteins of MAF family (the cellular counterpart viral oncogene MAF, isolated from avian musculoaponeurotic fibrosarcoma) are transcription factors regulating gene expression. On the bases size, they sub-grouped into two families: "large" (L-MAFs: MAFA, MAFB, c-MAF, and Nrl) "small" (S-MAFs: MAFF, MAFK, MAFG) (1).