COVID-19 severe pneumonia: Prospective multicentre study on demands on intensive care capacities

• DOI: 10.21101/cejph.a6672
• Publication Date: 2021-04-08T22:54:01Z
• Authors: Olga Džupová; Michal Moravec; Hynek Bartoš; Peter Brestovanský; Tomáš Tencer; Tomáš Hyánek; Jan Beroušek; Zdeňka Krupková; František Mošna; Tomáš Vymazal; Jiří Beneš
• Keywords: 2019-20 coronavirus outbreak; Betacoronavirus; Coronavirus Infections

Objectives: The aim of the study was to obtain data on demands intensive care capacities treat COVID-19 patients, and identify predictors for in-hospital mortality. Methods: prospective observational multicentre carried out from 1 March till 30 June 2020 included adult patients with confirmed SARS-CoV-2 infection respiratory failure requiring ventilatory support or high-flow nasal oxygen therapy (HFNO). Results: Seventy-four 46 males 28 females, median age 67.5 (Q1-Q3: 56-75) years, were included. Sixty-four (86.5%) had comorbidity. Sixty-six (89.2%) mechanically ventilated, four them received extracorporeal membrane oxygenation therapy. Eight (10.8%) treated non-invasive ventilation HFNO only. unit (ICU) stay 22.5 days. Eighteen (24.3%) needed continuous renal replacement Thirty (40.5%) died. Age acute kidney injury identified as independent death, chronic disease showed trend towards statistical significance poor outcome. Conclusions: Sufficient number beds, organ equipment well-trained staff is a decisive factor in managing epidemic. focused needs patients. Advanced When compared clinical course ICU management severe community-acquired pneumonia caused by other pathogens, we observed prolonged need support, high rate progression distress syndrome significant mortality studied population.