Demographic profile, clinical features, and outcome of peripapillary subretinal hemorrhage: an observational study

• DOI: 10.21203/rs.2.1848/v4
• Publication Date: 2020-04-09T19:50:43Z
• Authors: Ming Zou; Yi Zhang; Xi Huang; Sheng Gao; Junjun Zhang
• Keywords: Adult; Male; China; Adolescent; Fundus Oculi; Optic Disk; Valsalva retinopathy; Young Adult; 03 medical and health sciences; Sex Factors; 0302 clinical medicine; Myopia; Humans; Fluorescein Angiography; Child; Retrospective Studies; Age Factors; Retinal Hemorrhage; RE1-994; Prognosis; 3. Good health; Ophthalmology; Intrapapillary hemorrhage; Female; Morbidity; Peripapillary subretinal hemorrhage; Tomography, Optical Coherence; Research Article; Follow-Up Studies

Abstract Background: To evaluate the etiology, demographic profile, clinical features, and outcomes in patients with peripapillary subretinal hemorrhage (PSH).Methods: Thirty-eight eyes of 37 consecutive patients with PSH were enrolled in this prospective observational study over 4 years; all were followed for 2 years. The main outcome measures were demographic profile, possible etiology, clinical features, outcome, and prognosis.Results: Sixty-eight percent (26/38) of eyes were in female patients; the mean patient age was 20 years. Only 1 patient (1/37) showed bilateral involvement. All patients experienced acute onset of PSH. All eyes were myopic and their best-corrected visual acuities ranged from 20/1000 to 20/12.5. The fundus features of affected eyes were classified into 3 groups: (1) PSH alone (4/38 eyes, 10.5%); (2) PSH with intrapapillary hemorrhage (17/38 eyes, 44.7%); (3) PSH with intrapapillary and vitreous hemorrhage (17/38 eyes, 44.7%). PSH occurred in nasal edges of optic discs with a crescent shape and dull-red color. All affected optic discs were small and crowded, exhibiting variable degrees of tilting. The cup of affected optic discs was narrower and deeper than that of normal control discs. Other ancillary tests provided no additional value. After a mean follow-up of 2.85 months, the hemorrhages resolved spontaneously without sequelae. Recurrence of disease was not observed in any patients. Conclusions: PSH is common in myopic eyes with tilted optic discs. We suspect that these hemorrhages occurred as a result of abrupt movement acting on a morphologically vulnerable optic disc.