Combined effects of weight change trajectories and lifestyle factors on adiposity status at four years of age, a birth cohort study

• DOI: 10.21203/rs.2.19251/v1
• Publication Date: 2019-12-19T17:09:25Z
• Authors: Qingmin Lin; Yan-rui Jiang; Guang-hai Wang; Wan-qi Sun; Shu-mei Dong; Yu-jiao Deng; Min Meng; Qi Zhu; Hao Mei; Ying-chun Zhou; Jun Zhang; Peter E. Clayton; Karen Spruyt; Fan Jiang
• Keywords: Weight change

Abstract Background : Prior studies suggested that rapid weight change in infancy is associated with increased childhood and adulthood status. However, the trajectory early life over time extent to which lifestyle behaviors may modify risk of infant are not completely understood. Our aims were characterize explore its independent/combined effects factors on adiposity outcomes at four years age. Methods In our ongoing birth cohort study, we used nine follow-up points (birth, 3, 6, 9, 12, 18, 24 months, 4 years) calculate between two adjacent for age z-scores ( WAZ-change ), then define trajectories using group-based modeling. The each factor eating , physical activity, media exposure total sleep duration) measures determined multivariate regression (where applicable). Results A 84 (38.0%) children had a steady growth while other 137 (62.0%) an most notable during first six months. Compared growth, significantly higher status - body mass index (β = 0.93, 95% CI: 0.59, 1.37), waist circumference 1.90, 0.68, 3.12), subcutaneous fat 2.57, 1.13, 4.01). Moreover, only independent effect, but also combined effect measures. Conclusions We have identified distinct described their Larger samples longer period observation through needed replicate findings.