Decreased Retinal Microvasculature Densities in Pterygium

• DOI: 10.21203/rs.2.24138/v1
• Publication Date: 2020-02-20T21:02:50Z
• Authors: Feng Wang¹*; Lin-Hong Ye¹²*; Wen-Qing Shi¹; Biao Li¹; Qi Lin¹; You-Lan Min¹; Qing Yuan¹; Guiping Gao; Yi Shao¹#
• Keywords: Pterygium

Abstract Purpose To investigate the retinal vascular network alterations in eyes of patients with pterygium. Method 18 left from female pterygium and 18left 18female healthy control subjectswere enrolled.Optical coherence tomography angiography(OCTA) images were generated superficial retinallayer (SRL) deeper layer (DRL) macular retina for each eye. The microvascular(MIR) macrovascular (MAR) densities calculated MIR, MAR, total MIR (TMI) density was compared healthycontrol groups. Results In group,in SRL,the SMIR (superficial MIR), SR(superior right), IR(inferior R(right), SC(superficial central annuli)1, SC2 SC3decreased significantly maculararea (P<.05). Furthermore, all those decreased regions except R, negatively correlated disease course ( r=-0.6038 to -0.7762, P=0.0008), area size (r=-0.6043 -0.9508, P<0.05). For DRL, densityof DTMI, DMIR (deeper SR, IR, DC2 DC3 (r=-0.6901 -0.7795, P=0.0015), pterygium(r=-0.6043 -0.9563, No statistically significant differences correlation foundin other region (|r|＜0.47, P>0.05). Conclusion OCTA findings suggested that present density, which