Clinical Features and Prognosis of Gas-forming and Non-gas-forming Pyogenic Liver Abscess: A Comparative Study

• DOI: 10.21203/rs.2.24160/v1
• Publication Date: 2020-02-21T15:46:58Z
• Authors: Jia Zhang; Yi Gao; Zhaoqing Du; Yifan Ren; Jianbin Bi; Zheng Wu; Yi Lv; Rongqian Wu
• Keywords: pyogenic liver abscess; Microbiological culture

Abstract Background Gas-forming pyogenic liver abscess (GFPLA) accounts for up to 30% of all (PLA) cases. However, little is known the differences in clinical features and prognosis between GFPLA non-GFPLA. Aim This retrospective study compared Methods Data 392 patients with PLA treated from 1 January 2007 31 December 2016 were reviewed. was defined as gas abscess. Liver abscesses considered non- (n = 326) or 66). The outcomes relative that without GFPLA. Results groups similar gender ratio, age, smoking, drinking, coexistences. Klebsiella pneumoniae most common pathogenic bacteria, but negative rate bacterial culture non-GFPLA group significantly higher than GFPLA, had a previous abdominal surgery, especially hepatobiliary surgery. Compared group, percentage antibiotics combined percutaneous drainage higher, while percentages given alone surgical lower. rates sepsis pleural effusion, longer hospital stays did patients. No patient died during hospitalization. Conclusions associated past Patients history surgery should be monitored more closely early stage PLA. has high long It needs recognized distinct entity.