In Silico Investigation of a Local Hyperthermia Heating Device to Treat Pancreatic Cancer

• DOI: 10.2139/ssrn.4458991
• Publication Date: 2023-06-09T12:28:13Z
• Authors: Tom Quisenaerts; Luigi Brancato; Ivana Gorbašlieva; Dirk Ysebaert; John-Paul Bogers

An in silico model of a theoretical local hyperthermia device was created COMSOL®. In this the is placed around pancreas with aim treating pancreatic cancer. The would be through surgical access. It then used as means to treat cancer mild hyperthermia, conjunction standard care treatment. paper steps building COMSOL® are discussed. These include geometry, allocation material properties, implementation physics modules, meshing geometry and, finally, setup studies order run simulations. This modelled elevated temperature from 37.50 °C 38.40 core pancreas, using 42.00 heating device. According presented model, current design not capable tissues sufficient temperature. Limitations such simplified geometrical representations tail and representation surrounding tissues, were critically evaluated. contribution thermal parameters their implications should analysed for possible solutions future refinements model.