Facial Physiological Characteristics and Skin Microbiomes Changes are Associated with Body Mass Index (BMI)

• DOI: 10.2147/ccid.s447412
• Publication Date: 2024-03-04T09:25:18Z
• Authors: Laiji Ma; Huan Zhang; Qingwen Jia; Tianming Bai; Suzhen Yang; Man Wang; Yan Li; Li Shao
• Keywords: 0301 basic medicine; 03 medical and health sciences; Clinical, Cosmetic and Investigational Dermatology; malassezia; RL1-803; corynebacterium; microbiome; body mass index; Dermatology; skin physiological parameters; skin ph; Original Research

Background: Overweight and obesity have become public health problems worldwide. An increasing number of research works are focusing on skin physiology the manifestations obesity-associated diseases, but little is known about correlations between body mass index (BMI), facial physiological parameters, microbiome in healthy women. Objective: To investigate BMI, parameters bacteria fungi 198 women aged 18 to 35 years Shanghai. Methods: According international BMI standard Chinese reference standard, subjects were divided into three groups, "lean" B1, "normal" B2 "overweight" B3, measured by non-invasive instrumental methods, microbiota was analyzed 16S rRNA ITS high-throughput sequencing. Results: Compared with normal group, those overweight group exhibited a significant increase trans-epidermal water loss (TEWL), which indicated that barrier impaired. The haemoglobin content significantly increased, surface pH decreased high BMI. Furthermore, α-diversity, analysed using Shannon, Chao, Sobs, Ace indexes, increased suggesting diversity species abundance bacterial fungal also increased. Moreover, had higher abundances Streptococcus, Corynebacterium, Malassezia , Candida . Notably, negatively correlated relative Malassezia, Cladosporium Besides, positively associated Staphylococcus Corynebacterium Conclusion: These results indicate differences biophysical properties skin. A affects integrity changes flora composition. Keywords: index, microbiome, pH,