Clinical Misdiagnosis of Cutaneous Malignant Tumors as Melanocytic Nevi or Seborrheic Keratosis: A Retrospective Analysis of a Chinese Population

• DOI: 10.2147/ccid.s451288
• Publication Date: 2024-02-26T06:55:07Z
• Authors: Jun Zhang; Yu Wang; Wei Zhang; Linglong Cai; Jianglong Feng; Yiwei Zhu; Hongguang Lu
• Keywords: Seborrheic keratosis; Melanocytic nevus

The rising incidence and mortality associated with cutaneous malignant tumours highlight the importance of early diagnosis these tumors. In clinical practice, tumors are often misdiagnosed as benign skin lesions such melanocytic nevi (MN) seborrheic keratosis (SK) because their similar morphologic features. clinicopathological subtypes malignancies in East Asia populations significantly differ from those fair-skinned groups. However, studies on misdiagnoses Eastern countries lacking. Therefore, this study focused pathological features MN or SK a Chinese population. A total 4592 samples clinically diagnosed (n = 3503) 1089) July 2014 to June 2022 were collected evaluated retrospectively. data analyzed identify factors. Pathological assessments showed that 2.5% (86/3503) specimens malignancies, predominantly basal cell carcinoma (BCC, 84.9%, 73/86), followed by melanoma (MM, 8.1%, 7/86) squamous (SCC, 7.0%, 6/86). Similarly, 5.7% (62/1089) tumors, which BCC (50.0%, 31/62) was most common, SCC (41.9%, 26/62) MM (8.1%, 5/62). both types specimens, advanced age facial risk factors for malignancy misdiagnosis. rate, mean age, proportion higher than MN. Dermoscopy reduced rate misdiagnosis SK. China, not uncommon active introduction noninvasive diagnostic techniques is essential distinguish them.