<p>Diabetes mellitus is a predictive factor for radiation pneumonitis after thoracic radiotherapy in patients with lung cancer</p>

• DOI: 10.2147/cmar.s210095
• Publication Date: 2019-07-25T23:55:23Z
• Authors: Moonkyoo Kong; Yu Jin Lim; Youngkyong Kim; Mi Joo Chung; Soonki Min; Dong Oh Shin; Weonkuu Chung
• Keywords: Pneumonitis; Radiation Pneumonitis

We evaluated the effects of diabetes mellitus (DM) and DM-related serologic factors (HbA1c fasting glucose) on development radiation pneumonitis in patients with lung cancer.We retrospectively analyzed clinical data 123 cancer treated radiotherapy. Radiation was scored according to toxicity criteria Therapy Oncology Group. used binary logistic regression analysis find significant predictive for grade ≥3 pneumonitis.On univariable analysis, V20, mean dose, DM, HbA1c, glucose level were significantly associated pneumonitis. On multivariable remained The incidence 44.4% DM 20.7% without DM. 12.7% HbA1c ≤6.15% 41.5% >6.15%. 17.2% ≤121 mg/dL 35.5% >121 mg/dL.DM, are cancer. Patients who have >6.15%, should be greater caution.