<p>The combination of high bacterial count and positive biofilm formation is associated with the inflammation of pressure ulcers</p>

• DOI: 10.2147/cwcmr.s187733
• Publication Date: 2019-02-05T02:16:40Z
• Authors: Mao Kunimitsu; Gojiro Nakagami; Aya Kitamura; Yuko Mugita; Kaname Akamata; Sanae Sasaki; Chieko Hayashi; Yukie Mori; Hiromi Sanada
• Keywords: Bioburden; Bacterial colony; Negative-pressure wound therapy

Objective: Evaluating the bacterial bioburden of pressure ulcers through count and pathogenicity is important but currently difficult to perform in clinical setting. In order address this problem, we proposed two methods: 1) measurement using a quantitative device 2) detection biofilm formation by wound blotting. The purpose study was investigate relationship between bioburden, assessed combining these methods, presence inflammation. Patients participants cross-sectional were patients aged >20years with category II, III, IV, or unstageable examined during routine round an interdisciplinary ulcer team July 2014 April 2018. Relevant information, including count, formation, inflammation, collected from record. inflammation analyzed multilevel logistic regression analysis. Results: We included 273 samples obtained 98 patients. High significantly associated ( P =0.009) positive tended be =0.076). terms parameters, high (OR: 4.61, 95% CI: 1.37–15.46, =0.013). Conclusion: Assessment both parameters may provide more accurate evaluation contribute appropriate care. Keywords: infection, assessment, critical colonization, blotting, thermography