Pressing Intervention Promotes the Skeletal Muscle Repair of Traumatic Myofascial Trigger Points in Rats

• DOI: 10.2147/jpr.s333705
• Publication Date: 2021-10-17T20:44:33Z
• Authors: Quanrui Jiang; Xiang Feng; Dan Liu; Tao Li; Xiaoxia Kuang; Xiaowei Liu; Wu Li; Jiangshan Li
• Keywords: Myofascial pain

Objective: To observe the effect of pressing intervention on skeletal muscle repair myofascial trigger points (MTrPs) in rats and explore mechanism deactivation points. Methods: Thirty SPF were randomly divided into blank group, model group press with 10 each group. The MTrPs models established by blunt striking plus eccentric exercise, then evaluated. was given a self-made device for 14 days, other two groups fed normally. Soft tissue tension (STT) D 0.2 pressure pain threshold (PPT) measured before after intervention. at extracted assessed hematoxylin–eosin (HE) Masson staining. expression collagen I, III, α- smooth actin (α-SMA), myosin heavy chain (MHC) fibronectin (FN) detected Western Blotting. Enzyme linked immunosorbent assay (ELISA) used to evaluate substance P (SP), 5-hydroxytryptamine (5-HT), cyclooxygenase 2 (COX-2) prostaglandin E2 (PGE2). Results: (1) Compared PPT reduced (P < 0.05) group; while compared increased (2) showed obvious spontaneous potentials higher amplitude frequency, which also much than those 0.05). (3) HE staining results evident fibrosis larger area fibers relative that (4) amount FN, SMA, SP, 5-HT, COX-2 PGE2 content MHC decreased as all substances 0.05), instead Conclusion: Pressing can alleviate chronic inflammation, inhibit fibrosis, promote relieve pain. Keywords: pressing, points, muscle,