Environmental genomic surveillance of SARS-CoV-2 in wastewater in Rio de Janeiro, Brazil

• DOI: 10.2166/wh.2023.034
• Publication Date: 2023-05-10T12:08:32Z
• Authors: Andressa S. Gonça...; Mariana Magaldi; Beatriz Oliveira ...; Ana Paula Alves N...; Claudia Flores; Kaylanne S. Monte...; Maiara Lopes-Carv...; Aline Gimenez; Vinícius Souza Ca...; Vinícius Carneiro...; Camila Silva Quid...; Kayo Bianco; Maysa M. Clementino
• Keywords: Molecular Epidemiology; Epidemiological surveillance; 2019-20 coronavirus outbreak

Wastewater-based epidemiology can be a complementary approach for monitoring SARS-CoV-2 prevalence, diversity, and geographic distribution. It is regarding its prevalence The study aimed to evaluate the genetic diversity of in two wastewater treatment plants (WWTPs) Rio de Janeiro, Brazil. Samples were collected over period January December 2021 concentrated with PEG8000 presence was detected using E N1 genes. Partial sequencing genomes resulted identification variants concern interest throughout collection period. possible identify Mu, Delta, Gamma Omicron WWTP1; on contrary, no observed WWTP2. To best our knowledge, we variant Mu (B.1.621) containing characteristic mutations (S:E484K, S:N501Y) from WWTP, first time, Another clinical surveillance announced one month after finding. detection serve as tool monitor each community, helping understand spread virus among population.