A Typical Neurological Presentations in the ICU: Limbic Encephalitis

• DOI: 10.2174/1874828701306010040
• Publication Date: 2014-01-13T01:01:59Z
• Authors: Purvesh R. Patel
• Keywords: Limbic Encephalitis; Limbic system

Common neurological emergencies include overdose or withdrawal from illegal substance abuse, adverse effects of prescription medications, seizures, metabolic encephalopathy, infections and cerebrovascular accidents.Following a thorough clinical radiologic assessment, small group patients escape definitive diagnosis autoimmune encephalitides should be considered.Of these, limbic encephalitis (LE) is the most common may result paraneoplastic nonparaneoplastic sources.Common to both production antibodies targeting epitopes in brain parenchyma thought responsible for manifestations.Paraneoplastic Anti-N-methyl D-aspartate receptor (NMDAR) cause LE has gained awareness psychiatric literature.Paraneoplastic anti NMDAR typically presents young, previously healthy females with subacute onset symptoms, respiratory insufficiency, orofacial dyskinesias, autonomic instability seizures.Paraneoplastic induced by antibody against occult ovarian teratoma being inciting tumor.LE also been described association other tumors without tumors.The latter are known as primary disease.Diagnosis requires suspicion along prompt serum cerebrospinal fluid analysis detection.Immunotherapy remove suppress these resection an identified tumor therapy choice.This article will review presentation management who present medical intensive care unit.