Genotoxicity and cytotoxicity effects of x-rays on the oral mucosa epithelium at different fields of view: A cone beam computed tomography technique.

• DOI: 10.22088/cjim.14.1.121
• Publication Date: 2023-01-01
• Authors: Roghaieh Faeli Gh...; Hakimeh Ghorbani; Maryam Seyedmajidi; Kourosh Ebrahimne...; Ehsan Moudi; Seyedali Seyedmajidi
• Keywords: Karyorrhexis

Cone beam computed tomography (CBCT) is considered a common examination for dentistry problems. Cellular biology can be affected by exposure to ionizing radiations procedures. In this study, we aimed assess the genotoxicity and cytotoxicity effects of CBCT dental examinations at two different fields view (FOVs) in exfoliated buccal epithelial cells.Sixty healthy adults participated current study. They were divided into identical groups; with FOV 6*6 cm2 8*11 cm2. Exfoliated oral mucosa cells prepared immediately before after 10-12 days exposure. The cytological smears stained Papanicolaou technique. amounts micronuclei other cellular changes (Pyknosis, Karyolysis, Karyorrhexis) evaluated. variables parameters investigated FOVs performed using Wilcoxon test paired-samples t-test SPSS software.The cytotoxic both (6*6 cm2) increased significantly (p<0.001). Furthermore, significant difference (p<0.05) was observed between FOVs. Notably, had more side than that There no statistically among males females FOVs.CBCT disorders would increase risks inducing genetic damage. chromosomal damage cm2). regard, use must following ALARA principle.