Noninvasive Evaluation of Neural Impairment in Subjects With Impaired Glucose Tolerance

• DOI: 10.2337/dc08-1406
• Publication Date: 2008-10-04T00:55:09Z
• Authors: Zsuzsanna Putz; Ádám G Tabák; Nelli Tóth; Ildikó Istenes; Nóra Németh; Rajiv A. Gandhi; Zsolt Hermányi; Katalin Keresztes; György Jermendy; Solomon Tesfaye; Péter Kempler
• Keywords: Subclinical infection; Hypoesthesia

To evaluate neural dysfunction in subjects with impaired glucose tolerance (IGT).For this study, 46 IGT and 45 healthy volunteers underwent detailed neurological assessment. Cardiovascular autonomic function was assessed by standard cardiovascular reflex tests, heart rate variability characterized the triangle index. Sensory nerve using Neurometer (for current perception threshold) Medoc devices. Peak plantar pressure measured dynamic pedobarography, symptoms were graded neuropathy total symptom score.Subjects had significantly greater abnormalities detected four of five tests They a higher frequency both hyperesthesia hypoesthesia as threshold testing at 5 Hz, well increased heat detection thresholds.This study provides evidence that subclinical is present can be noninvasively. may contribute to risk subjects.