Major Depressive Disorder in Youths With IDDM: A controlled prospective study of course and outcome

• DOI: 10.2337/diacare.20.1.45
• Publication Date: 2007-03-05T22:51:27Z
• Authors: Maria Kovacs; D Scott Obrosky; David Goldston; Allan Drash
• Keywords: Depression; Longitudinal Study

OBJECTIVE To determine whether IDDM affects the course of major depressive disorder (MDD) in youths. RESEARCH DESIGN AND METHODS The study samples include 24 youths with (of a group 92) who developed MDD during longitudinal follow-up 10 years, on average, since onset medical condition, and 30 depressed psychiatric control subjects, matched relevant variables. Both groups were repeatedly assessed by semistructured interviews diagnosed operational criteria. RESULTS In diabetic median time to recovery from first episode was 6.4 months; 12 months onset, 69% will have recovered. Within 2 years recovery, 32% at risk for new episode; 6.5 altogether 47% are estimated recurrence. Only 37.5% subjects received treatment depression, 50% second episode. Overall rates recurrence indistinguishable groups. However, young women diabetes nine times greater recurrent depression than their male counterparts, eventually spent more being subjects. CONCLUSIONS characteristics appear be similar several regards. eventual propensity protracted depressions higher among suggest that mental health patients should closely monitored. findings confirm is undertreated primary care sector.