Kawasaki Disease: Four Case Reports of Cardiopathy with an Institutional and Literature Review

• DOI: 10.2350/06-10-0172.1
• Publication Date: 2007-11-13T16:33:19Z
• Authors: Amir H. Ashrafi; Jenny Wang; Christina A. Stoc...; David Lloyd; James B. McAlvin; Pierre Russo; Bahig M. Shehata
• Keywords: Systemic vasculitis; Etiology

Kawasaki disease (KD) is a systemic vasculitis condition with relatively unknown etiology. First described in 1967 by Tomisaku Japan, KD has come to be widely diagnosed every region of the world. The high prevalence children ages 6 months 5 years, particularly those Japanese descent. Patients often present fever, rash, lymphadenopathy, and conjunctival injections, but there no diagnostic test for KD. This paper presents data from our registry including 99 patients emphasis on cardiopathy. Three died complications KD, 1 patient underwent heart transplant massive aneurysmal dilatation. 4 explanted hearts showed spectrum pathological findings (acute thrombosis, vasculitis, myocarditis), long-term sequelae form Among survivors, 30% reviews most recent information regarding cardiopathy underlying molecular mechanisms.