Evaluation of the Regulatory Effect of Ripe Fruit Juice of <i>Saba senegalensis </i>on Hyperglycemia in <i>Rattus norvegicus</i>

• DOI: 10.24203/npg4ns87
• Publication Date: 2025-03-28T04:45:18Z
• Authors: Yao Yves Kouame; Abiba Gboko Ouattara; Yeboué Koffi Fran...

The objective of this study is to evaluate the ability of Saba senegalensis ripe fruit juice to regulate orally induced hyperglycemia in Rattus norvegicus. To do this, trace elements were first searched for in the juice of ripe fruit of Saba senegalensis by the calcination-mineralization method. Then, amino acids and vitamins C and B were searched for by the HPLC method. Finally, the evaluation of the regulatory activity of Saba senegalensis juice was done by induction of orally induced hyperglycemia after the ingestion of 75 grams of glucose. The results of this study reveal that the juice of ripe fruit of Saba senegalensis contains trace elements such as calcium, phosphorus, magnesium, potassium, sodium, manganese, zinc, copper and iron with respective contents of 1.20 ± 0.03; 0.42 ± 0.08; 0.95 ± 0.07; 1.40 ± 0.09; 0.09 ± 0.005; 0.27 ± 0.03; 0.96 ± 0.06; 0.94 ± 0.07 and 1.41 ± 0.02 μg/g dry matter. It also contains vitamins C and B1 as well as amino acids such as cysteine, proline and leucine, of which the latter is an essential amino acid. It appears from this study that Saba senegalensis fruit juice contains trace elements, amino acids and vitamins. The presence of these elements in the juice of ripe fruit of Saba senegalensis helps to lower the hyperglycemia induced by the consumption of glucose and to normalize blood sugar levels.