Immunolocalization of sodium-dependentglucose co-transporter 1 and sodium-dependent glucoseco-transporter 2 in chicken’s (Gallus gallus domesticus) kidneys

• DOI: 10.24425/pjvs.2024.149363
• Publication Date: 2024-09-20T06:55:09Z
• Authors: C. Allmang; P. Hussar; I. Dūrītis; T. Järveots
• Keywords: Gallus gallus domesticus

In homeostasis, which plays an important role in the proper functioning and maintenance of internal body, kidneys play a key being responsible for homeostasis glucose. Among glucose transporters, sodium-dependent co-transporters (SGLTs) have major kidney's ability to reabsorb Although localization these transporters has been extensively studied mammals, there are still gaps knowledge SGLTs birds different age groups. The aim this study was immunolocalize hen chickens ages SGLT1 SGLT2, comparing between derived from 32 (Gallus gallus domesticus) were devided equally into four groups: 3, 7, 14, 20 day old broilers, 8 indivuals each group. polyclonal primary antibodies Rabbit anti- anti-SGLT2 (Abcam, UK) used together with corresponding IHC kit UK). results visualized photographically using AxioCam HRc camera (Germany) connected Zeiss Axioplan-2 Imaging microscope (Germany). revealed similar immunolocalization SGLT2 apical part cells proximal renal tubules chickens' all Strong staining noted also cytoplasm epithelial straight convoluted tubules. Based on our study, kidney tissue newly hatched is ready immediately after hatching reabsorption transport, similarily that three-week-old chicks.