Effect of ration and exercise on plasma creatine kinase activity and lactate concentration in Thoroughbred horses with recurrent exertional rhabdomyolysis

• DOI: 10.2460/ajvr.2000.61.1390
• Publication Date: 2005-12-06T17:12:54Z
• Authors: Jennifer M. MacLeay; Stephanie J. Valberg; Joseph D. Pagan; Jinliang L. Xue; Flavio D. De La C...; Jennifer Roberts
• Keywords: Creatine kinase; Creatine

To determine the effects of 3 rations (low grain, fat, high grain) on plasma creatine kinase (CK) activity and lactate concentration in Thoroughbred horses with recurrent exertional rhabdomyolysis (RER).5 Thoroughbreds RER healthy (control horses).Rations were formulated to meet (low-grain fat rations) or exceed (high-grain ration) daily energy requirements. Each ration was fed a crossover design for weeks. Horses exercised treadmill Monday through Friday; maximum speed Friday 11 m/s (6% slope), Tuesday Thursday 9 m/s, Wednesday 4.5 m/s. Plasma CK determined before after exercise.Horses high-grain had significantly greater change 4 hours exercise, compared those low-grain ration. at trot canter increases activity, gallop. concentrations exercise similar control affected horses. Lactate not correlated RER.Rations grain requirements may increase episodes thoroughbred susceptible RER.