Peripheral polyneuropathy in a dog with functional islet B-cell tumor and widespread metastasis

• DOI: 10.2460/javma.1985.187.02.175
• Publication Date: 2025-02-06T18:18:13Z
• Authors: R. Shahar; C. Rousseaux; J. Steiss
• Keywords: Hindlimb; Exploratory laparotomy; Muscle Atrophy

A 12-year-old female Irish Setter was examined because of recurrent episodes hindlimb weakness. The dog not ataxic, but had generalized muscular atrophy, decreased patellar reflexes, and slow proprioception. Blood glucose content low (32 mg/dl) the amended insulin-glucose ratio high (9,600). Electromyographic studies showed evidence polyneuropathy. diagnosis functional islet B-cell tumor with peripheral neuropathy. Exploratory laparotomy performed. Widespread metastases were observed euthanatized poor prognosis. necropsied confirmed on basis microscopic findings.