Spatial Restriction within Intracranial Epidermoid Cysts Observed Using Short Diffusion-time Diffusion-weighted Imaging

• DOI: 10.2463/mrms.cr.2017-0111
• Publication Date: 2017-11-12T22:12:56Z
• Authors: Christina Andica; Masaaki Hori; Kouhei Kamiya; Saori Koshino; Akifumi Hagiwara; Koji Kamagata; Issei Fukunaga; Nozomi Hamasaki; Michimasa Suzuki; Thorsten Feiweier; Katsutoshi Murata; Atsushi Arakawa; Akihide Kondo; Osamu Akiyama; Shigeki Aoki
• Keywords: Histopathology; Epidermoid cyst

We report two cases of pathologically proven intracranial epidermoid cysts. Both were scanned with diffusion-weighted imaging using pulsed gradient spin-echo (PGSE) and oscillating (OGSE; 50 Hz) prototype sequences diffusion times 47.3 ms 8.5 ms, respectively. The apparent coefficient measured by OGSE was higher than that PGSE, indicating the spatial restriction water in laminated keratin layers within cyst as demonstrated histopathology.