The Final Stereogenic Unit of [2]Rotaxanes: Type 2 Geometric Isomers

• DOI: 10.26434/chemrxiv-2023-wc7sq-v2
• Publication Date: 2023-12-29T06:18:30Z
• Authors: Andrea Savoini; Peter Gallagher; Abed Saady; Stephen Goldup
• Keywords: Stereocenter; Rotaxane; Catenane

Mechanical stereochemistry arises when the interlocking of stereochemically trivial covalent subcomponents results in a stereochemical complex object. Although this general concept was identified 1961, description these molecules is still under development, with new mechanical stereoisomers recently. Here we present simple analysis rotaxane and catenane that allowed us to identify final missing stereogenic unit, an overlooked form geometric isomerism, demonstrate its stereoselective synthesis.